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近期荷兰发布了烟草和吸烟产品法规修正案,主要是建立一份针对烟草制品和电子烟禁用添加剂的清单（见下表），该修正案可能在2024年年初生效。
Annex 2
Substance (group) | CAS number(s) | TPD* Article | |
Tobacco products and e-cigarettes (TPD Articles 7.6a-e) | |||
1. Vitamins or additives that suggest health promotion (Vitamins or the following other additives, which are suggestive of health benefits or less health risks of the tobacco product) | 7.6a | ||
a) Vitamins | Not applicable | 7.6.a | |
Alpha-vitamin E | 59-02-9 | 7.6.a | |
Vitamin E (mixture of tocopherols andtocotrienols) | 1406-18-4 | 7.6.a | |
Vitamin C ascorbic acid | 50-81-7 | 7.6.a | |
Vitamin A | 68-26-8 | 7.6.a | |
Vitamin D3 | 67-97-0 | 7.6.a | |
Vitamin K | 12001-79-5 | 7.6.a | |
Vitamin B1 | 59-43-8 | 7.6.a | |
Vitamin B2 | 83-88-5 | 7.6.a | |
Niacin | 59-67-6 | 7.6.a | |
Pantothenic acid | 79-83-4 | 7.6.a | |
Vitamin B6 | 65-23-6 | 7.6.a | |
Folic acid | 59-30-3 | 7.6.a | |
Vitamin B12 | 68-19-9 | 7.6.a | |
Biotin | 58-85-5 | 7.6.a | |
b) Amino acids or modified amino acids | Not applicable | 7.6.a | |
L-alanine | 56-41-7 | 7.6.a | |
L-arginine | 74-79-3 | 7.6.a | |
GlycinL | 56-40-6 | 7.6.a | |
L--isoleucine | 443-79-8 | 7.6.a | |
L-leucine | 61-90-5 | 7.6.a | |
L-lysine | 56-87-1 | 7.6.a | |
Monohydrate | 39665-12-8 | 7.6.a | |
HCI | 657-27-2 | 7.6.a | |
L-phenylalanine | 63-91-2 | 7.6.a | |
L-proline | 147-85-3 | 7.6.a | |
L-serine | 56-45-1 | 7.6.a | |
L-threonine | 72-19-5 | 7.6.a | |
L-tyrosine | 60-18-4 | 7.6.a | |
L-valine | 72-18-4 | 7.6.a | |
L-cysteine | 52-89-1 | 7.6.a | |
L-5-hydroxytryptophan | 4350-09-8 | 7.6.a | |
S-adenosyl-methionine (SAM) | 485-80-3 | 7.6.a | |
Carnitine, total | Not applicable | 7.6.a | |
L-Carnitine | 541-15-1 | 7.6.a | |
L-Carnitine HCl | 6645-46-1 | 7.6.a | |
L-Carnitine L-tartrate | 36687-82-8 | 7.6.a | |
c) Flavonoids as well as antioxidative active phosholipids | Not applicable | 7.6.a | |
Naringin | 10236-47-2 | 7.6.a | |
d) Sodium selenite | 10102-18-8 | 7.6.a | |
2. Coffeine, taurine or the following other additives and stimulating additives and stimulating mixtures, associated with energy and vitatility | 7.6b | ||
a)Caffeine | 58-08-2 | 7.6.b | |
b)Taurine | 107-35-7 | 7.6.b | |
c)Maltodextrin | 9050-36-6 | 7.6.b | |
d) lngredients including processed ingredients, extracts and oils of the coffee plant and coffee bean | Not applicable | 7.6.b | |
Coffee bean oils | 8001-67-0 | 7.6.b | |
Coffee extract | 84650-00-0 | 7.6.b | |
Roasted coffee bean extract | 68916-18-7 | 7.6.b | |
Coffee, solid extract / French roast | 327-97-9 | 7.6.b | |
Coffee furanone | 3188-00-9 | 7.6.b | |
Coffee | 13708-12-8 | 7.6.b | |
e) Ingredients including processed ingredients, extracts and oils of the tea plant Camelia sinensis L. Kuntze | Not applicable | 7.6.b | |
Tea extract | 144207-58-9 | 7.6.b | |
f) lngredients including processed ingredients, extracts and oils of the guaranaplant / Paullinia cupana | Not applicable | 7.6.b | |
g)lngredients including processed ingredients, extracts and oils of the Yerbamate plant/ llex paraguayensis | Not applicable | 7.6.b | |
Yerba mate oils | 68916-96-1 | 7.6.b | |
Yerba mate extract | 73296-98-7 | 7.6.b | |
f) Thujone | 546-80-5 | 7.6.b | |
g)Sugars, including monosaccharides such as glucose fructose and galactose and sugar syrups (sugars including glucose, fructose and galactose and sugar-based syrups) | Not applicable | 7.6.b | |
D-Fructose | 57-48-7 | 7.6.b | |
D-Glucose | 50-99-7 | 7.6.b | |
monohydrate | 5996-10-1 | 7.6.b | |
lnvert sugar | 8013-17-0 | 7.6.b | |
Sucrose | 57-50-1 | 7.6.b | |
Glucose syrup (syrups, hydrolyzed starch) | 8029-43-4 | 7.6.b | |
3. Additives with colouring properties for the emissions | 7.6.c | ||
4. Following additives in smoking tobacco which facilitate inhalation or nicotine uptake | 7.6.d | ||
a)TRPM8 receptor agonists | Not applicable | 7.6.d | |
P-menthane 3- substituted and processed substances, including | Not applicable | 7.6.d | |
P-menthane-3-carboxamides, including p-menthane 3-N-alkyl carboxamides | Not applicable | 7.6.d | |
N-Ethyl-p-menthane-3-carboxamide (WS-3) | 39711-79-0 | 7.6.d | |
N-(Ethoxycarbonyl)methyl)-p-menthane-3-carboxamide (WS-5) | 68489-14-5 | 7.6.d | |
(1R,2S,5R)-N-(4-methoxyphenyl)-p menthane carboxamide (WS-12,CPS 112) | 68489-09-8 | 7.6.d | |
N-tert-butyl-p-menthane-3-carboxamide (WS-14) | unknown | 7.6.d | |
3N-(4-fluorophenyl)-p-menthane-3-carboxamide(CPS-124) | unknown | 7.6.d | |
CPS-125 | unknown | 7.6.d | |
N-(4-ethoxyphenyl)-p-menthane-3-carboxamide(CPS-128) | unknown | 7.6.d | |
CPS-3683 | unknown | 7.6.d | |
(-)-menthyl lactate | 59259-38-0 | 7.6.d | |
(-)-menthyl lactate | 61597-98-6 | 7.6.d | |
(-)-menthyl lactate | 17162-29-7 | 7.6.d | |
N-(p-menthane-3-carbonyl)-D-alanine ethyl ester(WS-109,CPS-369) | unknown | 7.6.d | |
2,3-dihydroxypropyl, p-menthane-3-carboxylate(WS-30) | 912452-14-3, 38706-03-5 | 7.6.d | |
Menthoxypropane-1,2-diol (MPD,Coolact-10) | 207792-35-6, 87061-04-9 | 7.6.d | |
Menthone 1,2-glycerol ketal | 563187-91-7 | 7.6.d | |
p-Menthan alcohols and associated esters | 7.6.d | ||
lcilin | 36945-98-9 | 7.6.d | |
Trimethyl isopropyl butanamide (WS-23) | 51115-67-4 | 7.6.d | |
lsopulegol, total | Not applicable | 7.6.d | |
lsopulegol | 7786-67-6 | 7.6.d | |
lsopulegol (Coolact P) | 89-79-2 | 7.6.d | |
1-(di-sec-butyl-phosphinoyl)-heptane (ws-148,CPS-148) | unknown | 7.6.d | |
Menthol | 1490-04-6 | 7.6.d | |
Menthol | 89-78-1 | 7.6.d | |
(-)-Menthol | 2216-51-5 | 7.6.d | |
(+)-Menthol | 15356-60-2 | 7.6.d | |
Menthone | 89-80-5 | 7.6.d | |
Menthone | 10458-14-7 | 7.6.d | |
Menthone | 491-07-6 | 7.6.d | |
(-)-Menthone | 14073-97-3 | 7.6.d | |
(+)-Menthone | 3391-87-5 | 7.6.d | |
L-Carvone | 6485-40-1 | 7.6.d | |
L-Carvone | 99-49-0 | 7.6.d | |
Geraniol | 106-24-1 | 7.6.d | |
Linalool | 78-70-6 | 7.6.d | |
1,8-Cineole, eucalyptol | 470-82-6 | 7.6.d | |
1,4-Cineole | 470-67-7 | 7.6.d | |
Hydroxycitronellal | 107-75-5 | 7.6.d | |
b) Following compounds prepared from plants: Oils and ingredients prepared from plants of the following genera, Mentha, Eucalyptus, Ocimum basilicum, Thymus and Salvia | Not applicable | 7.6.d | |
Mentha arvensis extract | 90063-97-1 | 7.6.d | |
Mentha arvensis oil | 68917-18-0 | 7.6.d | |
Mentha arvensis piperascens extract | 91722-84-8 | 7.6.d | |
Mentha piperita oil | 8006-90-4 | 7.6.d | |
Mentha piperita oil | 84082-70-2 | 7.6.d | |
Mentha pulegium | 8007-44-1 | 7.6.d | |
Mentha viridis oil | 8008-79-5 | 7.6.d | |
Eucalyptus globulus leaf oil | 8000-48-4 | 7.6.d | |
Eucalyptus globulus oiAl | 84625-32-1 | 7.6.d | |
Eucalyptus radiata oil | 92201-64-4 | 7.6.d | |
Ocimum basilicum/basil herb | 8015-73-4 | 7.6.d | |
Thyme | 8007-46-3 | 7.6.d | |
Thymol | 89-83-8 | 7.6.d | |
Salvia sclarea oil | 8016-63-5 | 7.6.d | |
Salvia sclarea extract | 84775-83-7 | 7.6.d | |
Salvia lavandulifolia extract | 90106-49-3 | 7.6.d | |
5. Following additives with CMR properties in unburned form | 7.6e | ||
a) Compounds classified according to part 3 of annex VI of regulation (EC) 1272/2008 as CMR category 1A, 1B or 2 | 7.6.e | ||
b) following other compounds: | |||
Birch tar oil, total | Not applicable | 7.6.e | |
Birch tar oil | 8001-88-5 | 7.6.e | |
Birch tar oil | 85940-29-0 | 7.6.e | |
Juniper tar | 8013-10-3 | 7.6.e | |
Sassafras oil | 8006-80-2 | 7.6.e | |
Sassafras wood | unknown | 7.6.e | |
sassafras leaves | unknown | 7.6.e | |
Sassafras bark | 84787-72-4 | 7.6.e | |
Methyleugenol | 93-15-2 | 7.6.e | |
Estragole | 140-67-0 | 7.6.e | |
Propylparabeen | 94-13-3 | 7.6.e | |
Titanium dioxide, total | Not applicable | 7.6.e | |
Titanium dioxide | 1317-70-0 | 7.6.e | |
Titanium dioxide | 1317-80-2 | 7.6.e | |
Titanium dioxide | 13463-67-7 | 7.6.e | |
Titanium dioxide | 51745-87-0 | 7.6.e | |
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